The medical grade alpha-hemi-
hydrate calcium sulfate is
critical for consistent bone
response in OSTEOSET pellets.
The crystalline structure,
composition, and particle size
distribution resulting from the
use of the alpha-hemihydrate
are the functional attributes
contributing to the controlled
resorption and uniform bone
response. However, the
complete mechanism of bone
formation with OSTEOSET is
currently being investigated.
The OSTEOSET manufacturing
process creates a uniform
crystalline structure of specific
size and shape resulting in a
controlled resorption rate con-
sistent with the rate of new
bone formation. This crystalline structure is found consistently only in OSTEOSET.
Other non-medical grade
calcium sulfates may resorb
too rapidly, preventing
creeping substitution of new
woven bone.
Conversely, slow resorption
of non-medical grade calcium
sulfate may inhibit new bone
growth.
Accordingly, the use of
common forms of calcium
sulfate have historically
resulted in sporadically
successful outcomes.
Non-medical grade
calcium sulfate
The figures show the
differences in the crystal
structure and shape of the
OSTEOSET alpha-hemihydrate
raw material (left) and other
available calcium sulfate
materials (right).
OSTEOSET
medical grade calcium sulfate
